About Pentasa

Using Pentasa Granules to treat Inflammatory Bowel Disease

Pentasa granules are a prescription medicine that treat mild to moderate Crohn’s Disease and Ulcerative Colitis.

Pentasa granules are tiny granules that contain mesalazine (also known as 5-aminosalicylic acid or 5-ASA). Mesalazine is an anti-inflammatory agent, similar to aspirin, and is thought to work by reducing inflammation in the bowel.

When Pentasa granules are swallowed they travel from the stomach through the small bowel and large bowel to the rectum, releasing mesalazine continuously as they go (called prolonged release), treating the inflammation.

How to take Pentasa Granules

  • Tear or cut to open the sachet along the dotted line.
  • Empty the contents (Pentasa granules) of the sachet onto the tongue and wash down with water or juice.
  • Swallow the Pentasa granules whole without chewing or crushing.

Follow all directions given to you by your Doctor or Pharmacist carefully.

If you do not understand the instructions on the packaging, ask your Doctor or Pharmacist for help.

Further information about Pentasa Granules

For further information about this medicine please refer to the Consumer Medicine Information (CMI).  The CMI contains information about what your medicine is, what it treats and how you should take it.  It also provides information on possible side effects and what you should do if you experience any of them.  Your Doctor and Pharmacist can provide the CMI to you or you can access it on the Medsafe website, www.medsafe.govt.nz.

Questions and Answers

  • Your Doctor will weigh up the risks and benefits, and assess the suitability of Pentasa, before prescribing for you.

    If you have any questions about taking Pentasa ask your Doctor or Pharmacist.

  • If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking Pentasa as you would normally. If you are not sure what to do, ask your Doctor or Pharmacist.

    If you have trouble remembering to take Pentasa ask your Pharmacist for some hints.

  • Unwanted side effects can occur with any medicine. Contact your Doctor if you experience any side effects when taking Pentasa.

  • Keep your Pentasa in the packaging until it is time to take your next dose. If you take Pentasa out of the packaging it may not keep well. Keep your Pentasa in a cool dry place where the temperature stays below 25°C.

    Refer to the CMI for further information.


  • NZ Datasheet
  • Pentasa Granules CMI
  • Pentasa Granules Pack Insert
  • How to Take Pentasa Granules Patient Leaflet